Structure of PDB 3g11 Chain A

Receptor sequence
>3g11A (length=411) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
KRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTSAYATKFAG
LVKDFNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIG
AAIGSGIGGLGLIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYG
LRGPSISIATAQTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGG
FGAARALSTRNDNPQAASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGA
KIYAELVGFGMSSDAYHMTSPPENGAGAALAMANALRDAGIEASQIGYVN
AHGTSTPAGDKAEAQAVKTIFGEAASRVLVSSTKSMTGHLLGAAGAVESI
YSILALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGMEYTLCNSFGFG
GTNGSLIFKKI
3D structure
PDB3g11 Synthesis and biological evaluation of platensimycin analogs.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q163 H303 E314 K335 H340 F398 F400
Catalytic site (residue number reindexed from 1) Q162 H302 E313 K334 H339 F397 F399
Enzyme Commision number 2.3.1.179: beta-ketoacyl-[acyl-carrier-protein] synthase II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P9C A Q163 A205 R206 T270 S271 P272 H303 T305 T307 P308 A309 G310 H340 F398 G399 F400 Q162 A204 R205 T269 S270 P271 H302 T304 T306 P307 A308 G309 H339 F397 G398 F399
Gene Ontology
Molecular Function
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0005515 protein binding
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0042803 protein homodimerization activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0009409 response to cold
GO:0019367 fatty acid elongation, saturated fatty acid
GO:0044281 small molecule metabolic process
GO:1903966 monounsaturated fatty acid biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3g11, PDBe:3g11, PDBj:3g11
PDBsum3g11
PubMed19233644
UniProtP0AAI5|FABF_ECOLI 3-oxoacyl-[acyl-carrier-protein] synthase 2 (Gene Name=fabF)

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