Structure of PDB 3g0w Chain A

Receptor sequence
>3g0wA (length=249) Species: 10116 (Rattus norvegicus) [Search protein sequence]
QPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA
KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLV
FNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVD
GLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPI
ARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
3D structure
PDB3g0w N-aryl-oxazolidin-2-imine muscle selective androgen receptor modulators enhance potency through pharmacophore reorientation.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LGB A L701 L704 N705 L707 W741 M742 M745 M749 F764 M780 F876 T877 L32 L35 N36 L38 W72 M73 M76 M80 F95 M111 F207 T208 MOAD: Ki=0.3nM
PDBbind-CN: -logKd/Ki=9.52,Ki=0.3nM
External links
PDB RCSB:3g0w, PDBe:3g0w, PDBj:3g0w
PDBsum3g0w
PubMed19351168
UniProtP15207|ANDR_RAT Androgen receptor (Gene Name=Ar)

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