Structure of PDB 3fzw Chain A

Receptor sequence
>3fzwA (length=127) Species: 303 (Pseudomonas putida) [Search protein sequence]
MNLPTAQEVQGLMARYIELVDVGDIEAIVQMYADDATVENPFGQPPIHGR
EQIAAFYRQGLGGGKVRACLTGPVRASHNGCGAMPFRVEMVWNGQPCALD
VINVMRFDEHGRIQTMQAYWSEVNLSV
3D structure
PDB3fzw Hydrogen bond coupling in the ketosteroid isomerase active site.
ChainA
Resolution1.32 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y16 N40 D100 N103
Catalytic site (residue number reindexed from 1) Y16 N40 D100 N103
Enzyme Commision number 5.3.3.1: steroid Delta-isomerase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 EQU A Y16 N40 F86 V88 L99 W120 Y16 N40 F86 V88 L99 W120
Gene Ontology
Molecular Function
GO:0004769 steroid delta-isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0008202 steroid metabolic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3fzw, PDBe:3fzw, PDBj:3fzw
PDBsum3fzw
PubMed19469568
UniProtP07445|SDIS_PSEPU Steroid Delta-isomerase (Gene Name=ksi)

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