Structure of PDB 3ftq Chain A

Receptor sequence
>3ftqA (length=254) Species: 10090 (Mus musculus) [Search protein sequence]
KGFEFTLMVVGESGLGKSTLINSLFKIERTVQIEASTVEIEERGVKLRLT
VVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGNRRHIIDNRVHCC
FYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRI
LDEIEEHSIKIYHLPDAEEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGK
KVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRS
ERLK
3D structure
PDB3ftq GTP-induced conformational changes in septins and implications for function
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A S51 T78 S18 T30
BS02 GNP A S46 G49 K50 S51 T52 T78 G104 K183 D185 V240 G241 R256 S13 G16 K17 S18 T19 T30 G56 K134 D136 V189 G190 R205 PDBbind-CN: -logKd/Ki=5.33,Kd=4.7uM
Gene Ontology
Biological Process
GO:0051301 cell division

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3ftq, PDBe:3ftq, PDBj:3ftq
PDBsum3ftq
PubMed19805342
UniProtP42208|SEPT2_MOUSE Septin-2 (Gene Name=Septin2)

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