Structure of PDB 3ft2 Chain A

Receptor sequence
>3ft2A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB3ft2 Steric hindrance and fast dissociation explain the lack of immunogenicity of the minor histocompatibility HA-1Arg Null allele.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 F9 E63 K66 V67 H70 V76 D77 Y84 R97 Y99 H114 T143 K146 W147 L156 Y159 L160 W167 Y171 Y7 F9 E63 K66 V67 H70 V76 D77 Y84 R97 Y99 H114 T143 K146 W147 L156 Y159 L160 W167 Y171
External links
PDB RCSB:3ft2, PDBe:3ft2, PDBj:3ft2
PDBsum3ft2
PubMed19342659
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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