Structure of PDB 3frc Chain A

Receptor sequence
>3frcA (length=201) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
IVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKDT
PFEQVPILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQ
DIHYKFNNTNLFKQNETTFLNEDLPKWSGYFEKLLKKNHTNNYYFVGNNL
TYADLAVFNLYDDIETKYPSSLKNFPLLKAHNEFISNLPNIKNYITNRKE
S
3D structure
PDB3frc Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y9 K15 R20
Catalytic site (residue number reindexed from 1) Y5 K11 R16
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0HG A F10 F45 Q58 V59 Q71 S72 N111 L115 F6 F41 Q54 V55 Q67 S68 N107 L111
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:3frc, PDBe:3frc, PDBj:3frc
PDBsum3frc
PubMed
UniProtQ8ILQ7|GST_PLAF7 Glutathione S-transferase (Gene Name=GST)

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