Structure of PDB 3fr9 Chain A

Receptor sequence
>3fr9A (length=200) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
MGDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKK
EKDTPFEQVPILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIF
CGVQDIHYKFNNTNLFETTFLNEDLPKWSGYFEKLLKKNHNDKYYFVGNN
LTYADLAVFNLYDDIETKYPSSLKNFPLLKAHNEFISNLPNIKNYITNRK
3D structure
PDB3fr9 Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118
ChainA
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y9 K15 R20
Catalytic site (residue number reindexed from 1) Y9 K15 R20
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A F10 F45 Q58 V59 Q71 S72 F10 F45 Q58 V59 Q71 S72
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:3fr9, PDBe:3fr9, PDBj:3fr9
PDBsum3fr9
PubMed
UniProtQ8ILQ7|GST_PLAF7 Glutathione S-transferase (Gene Name=GST)

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