Structure of PDB 3fqg Chain A

Receptor sequence
>3fqgA (length=313) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
MLREFSFYDVPPAHVPPVSEPLEIACYSLSRDRELLLDDSKLSYYYPPPL
FSDLNTGFPNRFHPPKSDPDPISIVKDVLMTKGIQMNSSFLTWRGLITKI
MCAPLDPRNHWETYLVMDPTSGIIMMEERTNQDRMCYWGYKFEAISTLPE
IWDAQDVVPDEQYCSIVKINIGKSKLILAGEVDCIWDKKPCENPNLHYVE
LKTSKKYPLENYGMRKKLLKYWAQSFLLGIGRIIIGFRDDNGILIEMKEL
FTHQIPKMLRPYFKPNDWTPNRLLVVLEHALEWIKQTVKQHPPSTEFTLS
YTGGSKLVLRQII
3D structure
PDB3fqg Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A E150 D201 E239 L240 E143 D183 E200 L201
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0004518 nuclease activity
GO:0005515 protein binding
GO:0019003 GDP binding
GO:0034353 mRNA 5'-diphosphatase activity
GO:0046872 metal ion binding
GO:0110152 RNA NAD+-cap (NAD+-forming) hydrolase activity
GO:0140432 5'-hydroxyl dinucleotide hydrolase activity
GO:1990174 phosphodiesterase decapping endonuclease activity
Biological Process
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0006397 mRNA processing
GO:0110155 NAD-cap decapping
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0090730 Las1 complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3fqg, PDBe:3fqg, PDBj:3fqg
PDBsum3fqg
PubMed19194460
UniProtO13836|DXO_SCHPO Decapping nuclease din1 (Gene Name=din1)

[Back to BioLiP]