Structure of PDB 3fon Chain A

Receptor sequence
>3fonA (length=274) Species: 10090 (Mus musculus) [Search protein sequence]
GSHSLRYFVTAVSRPGHGKPRYMEVGYVDDTEFVRFDSDAENPRYEPRTP
WMEQVEPEYWEGQTQIAKGNEQSSRVDLRTALRYYNQSAGGSHTIQRMRG
CEVGSDGRLLRGYQQVAYDGRDYIALNEDLKTWTAADMAALITKHKWEQA
GAAERDRAYLEGACVEWLRRYLELGNATLLRTDSPKAHVTHHSRPKDKVT
LRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVP
LGKEQNYTCHVYHEGLPEPLTLRW
3D structure
PDB3fon Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.
ChainA
Resolution2.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E24 Q63 I66 N70 D77 Y84 R97 R99 T143 K146 W147 A152 R155 Y159 W167 Y171 Y7 E24 Q63 I66 N70 D77 Y84 R97 R99 T143 K146 W147 A152 R155 Y159 W167 Y171
Gene Ontology
Biological Process
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
Cellular Component
GO:0016020 membrane
GO:0030670 phagocytic vesicle membrane
GO:0042612 MHC class I protein complex
GO:0098553 lumenal side of endoplasmic reticulum membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:3fon, PDBe:3fon, PDBj:3fon
PDBsum3fon
PubMed20093428
UniProtD2YW38

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