Structure of PDB 3fnn Chain A

Receptor sequence
>3fnnA (length=227) Species: 1718 (Corynebacterium glutamicum) [Search protein sequence]
EQVKLSVELIACSSFTPPADVEWSTDVEGAEALVEFAGRACYETFDKPNP
RTASNAAYLRHIMEVGHTALLEHANATMYIRGISRSATHELVRHRHFSFS
QLSQSEVVVPTLIDEDPQLRELFMHAMDESRFAFNELLNALEEKRKKQAR
QAARAVLPNATESRIVVSGNFRTWRHFIGMRASEHADVEIREVAVECLRK
LQVAAPTVFGDFEIETLADGSQMATSP
3D structure
PDB3fnn Biochemical and structural analysis of an atypical ThyX: Corynebacterium glutamicum NCHU 87078 depends on ThyA for thymidine biosynthesis
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.148: thymidylate synthase (FAD).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A S102 Q103 S100 Q101
Gene Ontology
Molecular Function
GO:0004799 thymidylate synthase activity
GO:0008168 methyltransferase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0050797 thymidylate synthase (FAD) activity
GO:0070402 NADPH binding
Biological Process
GO:0006231 dTMP biosynthetic process
GO:0006235 dTTP biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0032259 methylation

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3fnn, PDBe:3fnn, PDBj:3fnn
PDBsum3fnn
PubMed
UniProtP40111|THYX_CORGL Flavin-dependent thymidylate synthase (Gene Name=thyX)

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