Structure of PDB 3fiv Chain A

Receptor sequence
>3fivA (length=111) Species: 11673 (Feline immunodeficiency virus) [Search protein sequence]
TTTTLEKRPEILIFVNGYPIKFLLNTGADITILNRRDFQVKNSIENGRQN
MIGVGGGKRGTNYINVHLEIRDENYKTQCIFGNVCVLEDNSLIQPLLGRD
NMIKFNIRLVM
3D structure
PDB3fiv Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R13 L28 G32 A33 D34 M56 I57 G58 I98 R8 L23 G27 A28 D29 M51 I52 G53 I93
BS02 peptide A R13 N30 G32 A33 D34 I35 M56 I57 V59 I98 Q99 L101 R8 N25 G27 A28 D29 I30 M51 I52 V54 I93 Q94 L96
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3fiv, PDBe:3fiv, PDBj:3fiv
PDBsum3fiv
PubMed9271500
UniProtP16088|POL_FIVPE Pol polyprotein (Gene Name=pol)

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