Structure of PDB 3ffu Chain A

Receptor sequence
>3ffuA (length=133) Species: 959 (Bdellovibrio bacteriovorus) [Search protein sequence]
GHWIPVVAGFLRKDGKILVGQRPENNSLAGQWEFPGGKIENGETPEEALA
RELNEELGIEAEVGELKLACTHSYGDVGILILFYEILYWKGEPRAKHHMM
LEWIHPEELKHRNIPEANRKILHKIYKALGLEW
3D structure
PDB3ffu Structure and Biological Function of the RNA Pyrophosphohydrolase BdRppH from Bdellovibrio bacteriovorus.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.55: 8-oxo-dGTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP A V24 R40 E51 F52 G54 G55 K56 E70 I97 P133 N136 V6 R22 E33 F34 G36 G37 K38 E52 I79 P115 N118 PDBbind-CN: -logKd/Ki=6.44,Kd=0.36uM
BS02 MG A E70 E74 E52 E56
BS03 MG A G54 E74 G36 E56
Gene Ontology
Molecular Function
GO:0005525 GTP binding
GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0035539 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
GO:0042802 identical protein binding
GO:0044715 8-oxo-dGDP phosphatase activity
GO:0044716 8-oxo-GDP phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3ffu, PDBe:3ffu, PDBj:3ffu
PDBsum3ffu
PubMed19278661
UniProtQ6MPX4

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