Structure of PDB 3fea Chain A

Receptor sequence
>3feaA (length=83) Species: 9606 (Homo sapiens) [Search protein sequence]
QVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVY
CGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT
3D structure
PDB3fea Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes
ChainA
Resolution1.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M53 L56 G57 I60 M61 Y66 Q71 H72 V92 L98 M28 L31 G32 I35 M36 Y41 Q46 H47 V67 L73
BS02 peptide A Q26 V49 K50 T108 Q1 V24 K25 T83
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:3fea, PDBe:3fea, PDBj:3fea
PDBsum3fea
PubMed19153082
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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