Structure of PDB 3fdo Chain A

Receptor sequence
>3fdoA (length=90) Species: 9606 (Homo sapiens) [Search protein sequence]
IQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQ
HMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLAT
3D structure
PDB3fdo High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M53 L56 G57 I60 Y66 Q71 H72 V92 L98 M32 L35 G36 I39 Y45 Q50 H51 V71 L77
BS02 MG A Q43 Y55 Q22 Y34
BS03 MG A M53 H54 M32 H33
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:3fdo, PDBe:3fdo, PDBj:3fdo
PDBsum3fdo
PubMed19305137
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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