Structure of PDB 3fdm Chain A

Receptor sequence
>3fdmA (length=147) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRY
RRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALC
VESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNN
3D structure
PDB3fdm High-Resolution Structural Characterization of a Helical alpha/beta-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-x(L)
ChainA
Resolution2.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A A93 F97 Y101 F105 L108 V126 L130 D133 N136 W137 G138 R139 L194 Y195 N198 A42 F46 Y50 F54 L57 V75 L79 D82 N85 W86 G87 R88 L143 Y144 N147
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:3fdm, PDBe:3fdm, PDBj:3fdm
PDBsum3fdm
PubMed19229915
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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