Structure of PDB 3fas Chain A

Receptor sequence
>3fasA (length=260) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYK
IAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDF
SKPFMSLGISIMIKKGTPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKI
AVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQ
RKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVLDKLKN
KWWYDKGECG
3D structure
PDB3fas Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU A Y59 L88 T89 R94 G139 S140 T141 E191 Y59 L88 T89 R94 G139 S140 T141 E191 MOAD: Ki=171nM
PDBbind-CN: -logKd/Ki=6.77,Ki=171nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3fas, PDBe:3fas, PDBj:3fas
PDBsum3fas
PubMed19022251
UniProtP19493|GRIA4_RAT Glutamate receptor 4 (Gene Name=Gria4)

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