Structure of PDB 3f9b Chain A

Receptor sequence
>3f9bA (length=282) Species: 34055 (Yersinia enterocolitica (type O:9)) [Search protein sequence]
SPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCRR
QTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLA
SSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTI
REAGQKTISVPVVHVGNFPDQTAVSSEVTKALASLVDQTAETKRNMYESK
GSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQM
RVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
3D structure
PDB3f9b Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures.
ChainA
Resolution1.42 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E290 F354 D356 H402 C403 R409 T410
Catalytic site (residue number reindexed from 1) E104 F168 D170 H216 C217 R223 T224
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VO4 A R278 S388 S389 R92 S202 S203
BS02 PDV A C403 R404 A405 V407 G408 R409 Q446 Q450 C217 R218 A219 V221 G222 R223 Q260 Q264
Gene Ontology
Molecular Function
GO:0004725 protein tyrosine phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3f9b, PDBe:3f9b, PDBj:3f9b
PDBsum3f9b
PubMed19140798
UniProtP15273|YOPH_YEREN Tyrosine-protein phosphatase YopH (Gene Name=yopH)

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