Structure of PDB 3f7g Chain A

Receptor sequence
>3f7gA (length=99) Species: 9606 (Homo sapiens) [Search protein sequence]
AGATLSRGPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQD
KVRCFFCYGGLQSWKRGDDPWTEHAKWFPSCQFLLRSKGRDFVHSVQET
3D structure
PDB3f7g Orally bioavailable antagonists of inhibitor of apoptosis proteins based on an azabicyclooctane scaffold
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F81
Catalytic site (residue number reindexed from 1) F11
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C124 C127 H144 C151 C54 C57 H74 C81
External links
PDB RCSB:3f7g, PDBe:3f7g, PDBj:3f7g
PDBsum3f7g
PubMed19228017
UniProtQ96CA5|BIRC7_HUMAN Baculoviral IAP repeat-containing protein 7 (Gene Name=BIRC7)

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