Structure of PDB 3f70 Chain A

Receptor sequence
>3f70A (length=392) Species: 9606 (Homo sapiens) [Search protein sequence]
QDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNS
DAVLRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWC
AINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYPF
RQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDDDFWCHMWSPLIHP
VGWSRRVGHRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYL
MICVDDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKT
KSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLS
IHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEP
3D structure
PDB3f70 Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MLZ A D546 F570 W573 E608 D329 F353 W356 E391 MOAD: Kd=14uM
PDBbind-CN: -logKd/Ki=4.85,Kd=14uM
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:3f70, PDBe:3f70, PDBj:3f70
PDBsum3f70
PubMed19233876
UniProtQ969R5|LMBL2_HUMAN Lethal(3)malignant brain tumor-like protein 2 (Gene Name=L3MBTL2)

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