Structure of PDB 3f6x Chain A

Receptor sequence
>3f6xA (length=264) Species: 9031 (Gallus gallus) [Search protein sequence]
LAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLSPEAFLQ
EAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLR
LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLAR
LIEKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNR
EVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDY
FTSTEPQYQPGENL
3D structure
PDB3f6x Tuning a three-component reaction for trapping kinase substrate complexes.
ChainA
Resolution2.35 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D386 R388 A390 N391 D404 F424
Catalytic site (residue number reindexed from 1) D127 R129 A131 N132 D145 F155
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IHH A L273 A293 Y340 M341 G344 L393 D404 L19 A39 Y81 M82 G85 L134 D145
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:3f6x, PDBe:3f6x, PDBj:3f6x
PDBsum3f6x
PubMed19053485
UniProtP00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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