Structure of PDB 3f3m Chain A

Receptor sequence
>3f3mA (length=155) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
MEHTIAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKGTFSLEERMDL
IEQSVKHLPNVKVHQFSGLLVDYCEQVGAKTIIRGLRAVSDFEYELRLTS
MNKKLNNEIETLYMMSSTNYSFISSSIVKEVAAYRADISEFVPPYVEKAL
KKKFK
3D structure
PDB3f3m The structure of Staphylococcus aureus phosphopantetheine adenylyltransferase in complex with 3'-phosphoadenosine 5'-phosphosulfate reveals a new ligand-binding mode
ChainA
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H19 R92 S130
Catalytic site (residue number reindexed from 1) H19 R87 S125
Enzyme Commision number 2.7.7.3: pantetheine-phosphate adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PPS A G10 S11 G18 H19 R89 R92 Y99 I128 S129 S130 S131 G10 S11 G18 H19 R84 R87 Y94 I123 S124 S125 S126
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004595 pantetheine-phosphate adenylyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0015937 coenzyme A biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3f3m, PDBe:3f3m, PDBj:3f3m
PDBsum3f3m
PubMed19851003
UniProtP63820|COAD_STAAW Phosphopantetheine adenylyltransferase (Gene Name=coaD)

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