Structure of PDB 3f2r Chain A

Receptor sequence
>3f2rA (length=348) Species: 9606 (Homo sapiens) [Search protein sequence]
EQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLP
DTTATLGDEPRKVLLRLYGAMVLESVMFAILAERSLGPKLYGIFPQGRLE
QFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKY
LKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHND
CQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSY
EKYPFFRANIRKYPTKKQQLHFISSYLPAFQDFENLSTEEKSIIKEEMLL
EVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKL
3D structure
PDB3f2r Crystal structure of human choline kinase alpha in complex with hemicholinium-3
ChainA
Resolution2.35 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.1.32: choline kinase.
2.7.1.82: ethanolamine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HC6 A D306 Y333 Y354 F361 W420 W423 E434 F435 Y440 D200 Y227 Y248 F255 W313 W316 E327 F328 Y333
External links
PDB RCSB:3f2r, PDBe:3f2r, PDBj:3f2r
PDBsum3f2r
PubMed
UniProtP35790|CHKA_HUMAN Choline kinase alpha (Gene Name=CHKA)

[Back to BioLiP]