Structure of PDB 3f21 Chain A

Receptor sequence
>3f21A (length=67) Species: 9606 (Homo sapiens) [Search protein sequence]
LSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKK
GKLQKEAGTPPLWKIAV
3D structure
PDB3f21 The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K169 K170 N173 R174 Y177 T191 P192 P193 K37 K38 N41 R42 Y45 T59 P60 P61
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity

View graph for
Molecular Function
External links
PDB RCSB:3f21, PDBe:3f21, PDBj:3f21
PDBsum3f21
PubMed19074195
UniProtP55265|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (Gene Name=ADAR)

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