Structure of PDB 3exl Chain A

Receptor sequence
>3exlA (length=194) Species: 10090 (Mus musculus) [Search protein sequence]
QKTYQGNYGFHLGFLQSGTAKSVMCTYSPPLNKLFCQLAKTCPVQLWVSA
TPPAGSRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEG
NLYPEYLEDRQTFRHSVVVPYEPPEAGSEYTTIHYKYMCNSSCMGGMNRR
PILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKKE
3D structure
PDB3exl Crystal structure of a p53 core tetramer bound to DNA.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A S238 R270 A273 R277 S142 R174 A177 R181
BS02 ZN A C173 H176 C235 C239 C77 H80 C139 C143
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3exl, PDBe:3exl, PDBj:3exl
PDBsum3exl
PubMed18978813
UniProtP02340|P53_MOUSE Cellular tumor antigen p53 (Gene Name=Tp53)

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