Structure of PDB 3eug Chain A

Receptor sequence
>3eugA (length=225) Species: 37762 (Escherichia coli B) [Search protein sequence]
LTWHDVLAEEKQQPHFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELG
DVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPGFT
RPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQ
HREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFV
LANQWLEQHGETPIDWMPVLPAESE
3D structure
PDB3eug Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited.
ChainA
Resolution1.43 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D64 Y66 F77 H187
Catalytic site (residue number reindexed from 1) D60 Y62 F73 H183
Enzyme Commision number 3.2.2.27: uracil-DNA glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GOL A D64 Y66 A76 N123 H187 D60 Y62 A72 N119 H183
BS02 GOL A K15 F45 F48 K11 F41 F44
Gene Ontology
Molecular Function
GO:0004844 uracil DNA N-glycosylase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair
GO:0097510 base-excision repair, AP site formation via deaminated base removal
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:3eug, PDBe:3eug, PDBj:3eug
PDBsum3eug
PubMed10090282
UniProtP12295|UNG_ECOLI Uracil-DNA glycosylase (Gene Name=ung)

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