Structure of PDB 3epe Chain A

Receptor sequence
>3epeA (length=257) Species: 10116 (Rattus norvegicus) [Search protein sequence]
TVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIA
IVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSK
PFMSLGISIMIKKGTPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAV
YEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYTEQRK
PCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVLDKLKNKW
WYDKGEC
3D structure
PDB3epe Correlating AMPA receptor activation and cleft closure across subunits: crystal structures of the GluR4 ligand-binding domain in complex with full and partial agonists
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GLU A Y57 L86 T87 R92 G137 S138 T139 E189 Y57 L86 T87 R92 G137 S138 T139 E189
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:3epe, PDBe:3epe, PDBj:3epe
PDBsum3epe
PubMed19102704
UniProtP19493|GRIA4_RAT Glutamate receptor 4 (Gene Name=Gria4)

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