Structure of PDB 3eov Chain A

Receptor sequence
>3eovA (length=166) Species: 5661 (Leishmania donovani) [Search protein sequence]
EPEVTAKVYFDVMIDSEPLGRITIGLFGKDAPLTTENFRQLCTGEHGFGY
KDSIFHRVIQNFMIQGGDFTNFDGTGGKSIYGEKFADENLNVKHFVGALS
MANAGPNTNGSQFFITTAPTPWLDGRHVVFGKVLDGMDVVLRIEKTKTNS
HDRPVKPVKIVASGEL
3D structure
PDB3eov Structure of Cyclophilin from Leishmania Donovani Bound to Cyclosporin at 2.6 A Resolution: Correlation between Structure and Thermodynamic Data.
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R78 F83 Q86 N124 F135 L144 H148
Catalytic site (residue number reindexed from 1) R57 F62 Q65 N103 F114 L123 H127
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R78 F83 Q86 G95 A123 N124 Q133 F135 W143 H148 R57 F62 Q65 G74 A102 N103 Q112 F114 W122 H127
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:3eov, PDBe:3eov, PDBj:3eov
PDBsum3eov
PubMed19923714
UniProtQ9U9R3

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