Structure of PDB 3eno Chain A

Receptor sequence
>3enoA (length=329) Species: 2303 (Thermoplasma acidophilum) [Search protein sequence]
AMDPMIVLGLEGTAHTISCGIIDESRILAMESSMYRPKTGGIRPLDAAVH
HSEVIDTVISRALEKAKISIHDIDLIGFSMGPGLAPSLRVTATAARTISV
LTGKPIIGVNHPLGHIEIGRRVTGAIDPVMLYVSGGNTQVIAHVNGRYRV
LGETLDIGIGNMIDKFAREAGIPFPGGPEIEKLAMKGTKLLDLPYSVKGM
DTAFSGILTAALQYLKTGQAIEDISYSIQETAFAMLVEVLERALYVSGKD
EILMAGGVALNRRLRDMVTNMAREAGIRSYLTDREYCMDNGIMIAQAALL
MYKSGVRMSVEETAVNPRFRIDEVDAPWI
3D structure
PDB3eno Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
ChainA
Resolution3.0201 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.234: N(6)-L-threonylcarbamoyladenine synthase.
2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A H107 H111 Y128 D285 H111 H115 Y132 D289
Gene Ontology
Biological Process
GO:0002949 tRNA threonylcarbamoyladenosine modification
Cellular Component
GO:0000408 EKC/KEOPS complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:3eno, PDBe:3eno, PDBj:3eno
PDBsum3eno
PubMed18951093
UniProtQ9HLA5|KAE1B_THEAC Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein (Gene Name=Ta0324)

[Back to BioLiP]