Structure of PDB 3ek5 Chain A

Receptor sequence
>3ek5A (length=241) Species: 340 (Xanthomonas campestris pv. campestris) [Search protein sequence]
NAMSELSYRRILLKLSGEALMGDGDYGIDPKVINRLAHEVIEAQQAGAQV
ALVIGGGNIFRGAGLAASGMDRVTGDHMGMLATVINALAMQDALEKLGAK
VRVMSAIKINDVCEDFIRRRAIRHLEKGRIAIFAAGTGNPFFTTDSGAAL
RAIEIGADLLLKATKVDGVYDKDPKKHSDAVRYDSLTYDEVIMQGLEVMD
TAAFALARDSDLPLRIFGMSEPGVLLRILHGAQIGTLVQGR
3D structure
PDB3ek5 Unique GTP-Binding Pocket and Allostery of Uridylate Kinase from a Gram-Negative Phytopathogenic Bacterium
ChainA
Resolution2.56 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.4.22: UMP kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP A R100 N108 D109 V110 C111 E112 R118 R127 R102 N110 D111 V112 C113 E114 R120 R129
BS02 GTP A I115 R117 R118 R121 K125 I117 R119 R120 R123 K127
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0009041 UMP/dUMP kinase activity
GO:0016301 kinase activity
GO:0033862 UMP kinase activity
Biological Process
GO:0006221 pyrimidine nucleotide biosynthetic process
GO:0006225 UDP biosynthetic process
GO:0016310 phosphorylation
GO:0044210 'de novo' CTP biosynthetic process
GO:0046940 nucleoside monophosphate phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:3ek5, PDBe:3ek5, PDBj:3ek5
PDBsum3ek5
PubMed19059268
UniProtP59009|PYRH_XANCP Uridylate kinase (Gene Name=pyrH)

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