Structure of PDB 3egs Chain A

Receptor sequence

>3egsA (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]

ALQLTQSPSSLSASVGDRITITCRASQGVTSALAWYRQKPGSPPQLLIYD
ASSLESGVPSRFSGSGSGTEFTLTISTLRPEDFATYYCQQLHFYPHTFGG
GTRVDVRRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKV
DNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYECEVTHQG
LSSPVTKSFNRGE

3D structure

PDB

3egs Structural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5.

Chain

Resolution

3.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	L91 H92 F93 Y94 H96	L91 H92 F93 Y94 H96

External links

PDB	RCSB:3egs, PDBe:3egs, PDBj:3egs
PDBsum	3egs
PubMed	19754136

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