Structure of PDB 3efo Chain A

Receptor sequence
>3efoA (length=716) Species: 9606 (Homo sapiens) [Search protein sequence]
TYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLP
PIQYEPVLCSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPSYAGIS
ELNQPAELLPQFSSIEYVVLRGPQMPLIFLYVVDTCMEDEDLQALKESMQ
MSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTGDLSAKQLQE
MLGLSKVSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVAL
SIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTPIRSWHDIDK
DNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTG
GYMVMGDSFNTSLFKQTFQRVFTKDMHGQFKMGFGGTLEIKTSREIKISG
AIGPCVSLNSKGPCVSENEIGTGGTCQWKICGLSPTTTLAIYFEVVGRGA
IQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMAR
LAIYRAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPSSFRFSETFSLYP
QFMFHLRRSSFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSF
SGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEY
ENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVPILTDD
VSLQVFMDHLKKLAVS
3D structure
PDB3efo Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C61 C66 C85 C88 C59 C64 C83 C86
Gene Ontology
Molecular Function
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0072659 protein localization to plasma membrane
GO:0090110 COPII-coated vesicle cargo loading
GO:0090114 COPII-coated vesicle budding
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0012507 ER to Golgi transport vesicle membrane
GO:0016020 membrane
GO:0030127 COPII vesicle coat
GO:0030134 COPII-coated ER to Golgi transport vesicle
GO:0031410 cytoplasmic vesicle
GO:0048471 perinuclear region of cytoplasm
GO:0070971 endoplasmic reticulum exit site

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3efo, PDBe:3efo, PDBj:3efo
PDBsum3efo
PubMed18843296
UniProtQ15436|SC23A_HUMAN Protein transport protein Sec23A (Gene Name=SEC23A)

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