Structure of PDB 3ef0 Chain A

Receptor sequence
>3ef0A (length=361) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
RLESENVKRLRQEKRLSLIVDLDQTIIHATVDPTVGEWMSDPGNVNYDVL
RDVRSFNLQEGPSGYTSCYYIKFRPGLAQFLQKISELYELHIYTMGTKAY
AKEVAKIIDPTGKLFQDRVLSRDDSGSLAQKSLRRLFPCDTSMVVVIDDR
GDVWDWNPNLIKVVPYEFFVGIGDINSALEEQNKERVTALELQKSERPLA
KQQNALLEDEGKPTPSHTLLHNRDHELERLEKVLKDIHAVYYEEENDISS
RSGNHKHANVGLIIPKMKQKVLKGCRLLFSGVIPLGVDVLSSDIAKWAMS
FGAEVVLDFSVPPTHLIAAKIRTEKVKKAVSMGNIKVVKLNWLTESLSQW
KRLPESDYLLY
3D structure
PDB3ef0 The structure of Fcp1, an essential RNA polymerase II CTD phosphatase.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ALF A D170 L171 D172 T243 M244 K280 D21 L22 D23 T94 M95 K131
BS02 MG A D170 D172 D298 D21 D23 D149
Gene Ontology
Molecular Function
GO:0004721 phosphoprotein phosphatase activity
GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Cellular Component
External links
PDB RCSB:3ef0, PDBe:3ef0, PDBj:3ef0
PDBsum3ef0
PubMed19026779
UniProtQ9P376|FCP1_SCHPO RNA polymerase II subunit A C-terminal domain phosphatase (Gene Name=fcp1)

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