Structure of PDB 3ebc Chain A

Receptor sequence
>3ebcA (length=241) Species: 727 (Haemophilus influenzae) [Search protein sequence]
SFIKPIYQDINSILIGQKVGEPFEKLVYKFLKENLSDLTFKQYEYLNDLF
MKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTAD
ILLVKDQFYELLDVKTRNIAQAPAIISAYKLAQTCAKMIDNKEFDLFDIN
YLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQ
GFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL
3D structure
PDB3ebc Early Interrogation and Recognition of DNA Sequence by Indirect Readout
ChainA
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R91 G92 K93 N110 Y199 N201 R241 K248 R77 G78 K79 N96 Y182 N184 R224 K231
BS02 dna A Q109 N110 Q138 S144 Y146 K147 A205 M206 Q207 Q95 N96 Q121 S127 Y129 K130 A188 M189 Q190
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function

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Biological Process
External links
PDB RCSB:3ebc, PDBe:3ebc, PDBj:3ebc
PDBsum3ebc
PubMed19081059
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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