Structure of PDB 3e7x Chain A

Receptor sequence
>3e7xA (length=508) Species: 1423 (Bacillus subtilis) [Search protein sequence]
MKLLHAIQTHAETYPQTDAFRSQGQSLTYQELWEQSDRAAAAIQKRISGE
KKSPILVYGHMEPHMIVSFLGSVKAGHPYIPVDLSIPSERIAKIIESSGA
ELLIHAAGLSIDAVGQQIQTVSAEELLENEGGSVSQDQWVKEHETFYIIY
TSGSTGNPKGVQISAANLQSFTDWICADFPVSGGKIFLNQAPFSFDLSVM
DLYPCLQSGGTLHCVTKDAVNKPKVLFEELKKSGLNVWTSTPSFVQMCLM
DPGFSQDLLPHADTFMFCGEVLPVSVAKALLERFPKAKIFNTYGPTEATV
AVTSVEITNDVISRSESLPVGFAKPDMNIFIMDEEGQPLPEGEKGEIVIA
GPSVSRGYLGEPELTEKAFFSHEGQWAYRTGDAGFIQDGQIFCQGRLDFQ
IKLHGYRMELEEIEFHVRQSQYVRSAVVIPYQPNGTVEYLIAAIVPEEHE
FEKEFQLTSAIKKELAASLPAYMIPRKFIYQDHIQMTANGKIDRKRIGEE
VLVRSHHH
3D structure
PDB3e7x Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T151 F171 T296 E297 K402 R407 K491
Catalytic site (residue number reindexed from 1) T151 F171 T296 E297 K402 R407 K491
Enzyme Commision number 6.2.1.54: D-alanine--[D-alanyl-carrier protein] ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A G269 E270 V271 T292 Y293 P295 T296 D382 K402 R407 G269 E270 V271 T292 Y293 P295 T296 D382 K402 R407
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0047473 D-alanine [D-alanyl carrier protein] ligase activity
Biological Process
GO:0070395 lipoteichoic acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3e7x, PDBe:3e7x, PDBj:3e7x
PDBsum3e7x
PubMed18784082
UniProtP39581|DLTA_BACSU D-alanine--D-alanyl carrier protein ligase (Gene Name=dltA)

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