Structure of PDB 3e6y Chain A

Receptor sequence
>3e6yA (length=234) Species: 4097 (Nicotiana tabacum) [Search protein sequence]
PTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVA
YKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICD
GILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAEST
LTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQA
FDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWT
3D structure
PDB3e6y A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R63 R136 Y137 L181 N182 V185 E189 N233 L236 W237 R59 R132 Y133 L177 N178 V181 E185 N229 L232 W233
BS02 CW1 A N49 F126 K129 P174 D222 N45 F122 K125 P170 D218 MOAD: Kd=2.5uM
PDBbind-CN: -logKd/Ki=5.60,Kd=2.5uM
Gene Ontology
Biological Process
GO:0007165 signal transduction
GO:0008104 protein localization
Cellular Component
GO:0005737 cytoplasm

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3e6y, PDBe:3e6y, PDBj:3e6y
PDBsum3e6y
PubMed19244612
UniProtP93343|1433C_TOBAC 14-3-3-like protein C

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