Structure of PDB 3e41 Chain A

Receptor sequence
>3e41A (length=246) Species: 727 (Haemophilus influenzae) [Search protein sequence]
SFIKPIYQDINSILIGQKVKRPAGEPFEKLVYKFLKENLSDLTFKQYEYL
NDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQN
DTADILLVKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKE
FDLFDINYLEVDWELNGDLVCVSTSFAELFKSEPSELYINWAAAMQIQFH
VRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI
3D structure
PDB3e41 DNA distortion and specificity in a sequence-specific endonuclease.
ChainA
Resolution2.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A G92 K93 K108 F138 Y199 A203 A204 R241 G82 K83 K98 F128 Y188 A192 A193 R230
BS02 dna A Q109 N110 D111 D127 K129 T130 S136 F138 A139 P140 N141 S144 K147 A205 Q207 Q99 N100 D101 D117 K119 T120 S126 F128 A129 P130 N131 S134 K137 A194 Q196
BS03 CA A D114 D127 V128 D104 D117 V118
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:3e41, PDBe:3e41, PDBj:3e41
PDBsum3e41
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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