Structure of PDB 3e3y Chain A

Receptor sequence
>3e3yA (length=242) Species: 727 (Haemophilus influenzae) [Search protein sequence]
SFIKPIYQDINSILIGQKVKRFEKLVYKFLKENLSDLTFKQYEYLNDLFM
KNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKNDTADIL
LVKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEFDLFDI
NYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLD
QGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL
3D structure
PDB3e3y DNA distortion and specificity in a sequence-specific endonuclease.
ChainA
Resolution2.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A G92 K93 F138 Y199 N201 A203 R241 G77 K78 F122 Y183 N185 A187 R225
BS02 dna A N110 D111 V128 K129 T130 S136 A137 F138 P140 N141 S144 K147 A205 Q207 N94 D95 V112 K113 T114 S120 A121 F122 P124 N125 S128 K131 A189 Q191
BS03 CA A D114 D127 V128 D98 D111 V112
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function

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Biological Process
External links
PDB RCSB:3e3y, PDBe:3e3y, PDBj:3e3y
PDBsum3e3y
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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