Structure of PDB 3e25 Chain A

Receptor sequence
>3e25A (length=270) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
TTWHRPGWTIGELEAAKAGRTISVVLPALNEEATIESVIDSISPLVDGLV
DELIVLDSGSTDDTEIRAIASGARVVSREQALPEVPVRPGKGEALWRSLA
ATSGDIVVFIDSDLINPHPLFVPWLVGPLLTGEGIQLVKSFYRRVTELVA
RPLLAALRPELGCVLQPLSGEYAASRELLTSLPFAPGYGVEIGLLIDTFD
RLGLDAIAQVNLGVRNRPLDELGAMSRQVIATLLSRCGIPDSGVGLTQFY
TRHTWPVSLVDRPPMKVMRP
3D structure
PDB3e25 Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.266: glucosyl-3-phosphoglycerate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UDP A A51 L52 E54 S81 G113 K114 D134 S135 D136 Y229 R261 M269 A28 L29 E31 S58 G90 K91 D111 S112 D113 Y188 R217 M225
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006011 UDP-glucose metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3e25, PDBe:3e25, PDBj:3e25
PDBsum3e25
PubMed19015727
UniProtP9WMW9|GPGS_MYCTU Glucosyl-3-phosphoglycerate synthase (Gene Name=gpgS)

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