Structure of PDB 3e1z Chain A

Receptor sequence
>3e1zA (length=109) Species: 5693 (Trypanosoma cruzi) [Search protein sequence]
SHKVTKAHNGATLTVAVGELVEIQLPSNPTTGFAWYFEGGTKESPNESMF
TVENKYFPPDSKLLGAGGTEHFHVTVKAAGTHAVNLTYMRPWTGPSHDSE
RFTVYLKAN
3D structure
PDB3e1z Crystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteases.
ChainA
Resolution1.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A E23 H72 H74 E22 H71 H73
Gene Ontology
Molecular Function
GO:0004869 cysteine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0010466 negative regulation of peptidase activity
Cellular Component
GO:0009986 cell surface
GO:0020016 ciliary pocket
GO:0031410 cytoplasmic vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3e1z, PDBe:3e1z, PDBj:3e1z
PDBsum3e1z
PubMed19143838
UniProtQ966X9|CHAG_TRYCR Chagasin (Gene Name=cha)

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