Structure of PDB 3dxd Chain A

Receptor sequence
>3dxdA (length=131) Species: 9606 (Homo sapiens) [Search protein sequence]
NELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVA
PATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHM
FWCEPNAASLSEAVQAACMLRYQKCLDARSQ
3D structure
PDB3dxd Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
ChainA
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V559 R607 L609 S610 F611 L612 A613 V614 G615 R616 V618 A644 E648 Q651 C654 M655 R657 Y658 C661 R665 V23 R71 L73 S74 F75 L76 A77 V78 G79 R80 V82 A108 E112 Q115 C118 M119 R121 Y122 C125 R129
Gene Ontology
Molecular Function
GO:0001540 amyloid-beta binding

View graph for
Molecular Function
External links
PDB RCSB:3dxd, PDBe:3dxd, PDBj:3dxd
PDBsum3dxd
PubMed18833287
UniProtO00213|APBB1_HUMAN Amyloid beta precursor protein binding family B member 1 (Gene Name=APBB1)

[Back to BioLiP]