Structure of PDB 3dsd Chain A

Receptor sequence
>3dsdA (length=333) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
MKFAHLADIHLGYEQFHKPQREEEFAEAFKNALEIAVQENVDFILIAGDL
FHSSRPSPGTLKKAIALLQIPKEHSIPVFAIEGNSDRTQRGPSVLNLLED
FGLVYVIGMRKEKVENEYLTSERLGNGEYLVKGVYKDLEIHGMKYMSSAW
FEANKEILKRLFRPTDNAILMLHQGVREVSEARGEDYFEIGLGDLPEGYL
YYALGHIHKRYETSYSGSPVVYPGSLERWDFGDYEVRYEWDGIKFKERYG
VNKGFYIVEDFKPRFVEIKVRPFIDVKIKGSEEEIRKAIKRLIPLIPKNA
YVRLNIGWRKPFDLTEIKELLNVEYLKIDTWRI
3D structure
PDB3dsd Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R55 R87 Q89 R90 S147 W150 R55 R87 Q89 R90 S147 W150
BS02 MN A D8 H10 D49 H208 D8 H10 D49 H208
BS03 MN A D49 N84 H173 H206 D49 N84 H173 H206
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
Biological Process
GO:0000729 DNA double-strand break processing
GO:0006302 double-strand break repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3dsd, PDBe:3dsd, PDBj:3dsd
PDBsum3dsd
PubMed18854158
UniProtQ8U1N9|MRE11_PYRFU DNA double-strand break repair protein Mre11 (Gene Name=mre11)

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