Structure of PDB 3drw Chain A

Receptor sequence
>3drwA (length=460) Species: 53953 (Pyrococcus horikoshii) [Search protein sequence]
SGRENLYFQGMIPEHLSIYTAYNANIAAIVKLNQETIQNLINAFDPDEVK
RRIEEYPREINEPIDFVARLVHTLKLGKPAAVPLVNEKMNEWFDKTFRYE
EERLGGQAGIIANTLAGLKIRKVIAYTPFLPKRLAELFKKGVLYPVVENG
ELQFKPIQEAYREGDPLKINRIFEFRKGLKFKLGDETIEIPNSGRFIVSA
RFESISRIETREDIKPFLGEIGKEVDGAIFSGYQGLRTKYSDGKDANYYL
RRAKEDIIEFKEKDVKIHVEFASVQDRKLRKKIITNILPFVDSVGIDEAE
IAQILSVLGYRELADRIFTYNRLEDSILGGMIILDELNFEILQVHTTYYL
MYITHRDNPLSEEELAKSLEFGTTLAAARASLGDIRGPDDYKVGLKVPFN
ERSEYVKLRFEEAKSRLRMREYKVVVIPTRLVQNPVLTVGLGDTISAGAF
LTYLEFLKRH
3D structure
PDB3drw ADP-dependent 6-phosphofructokinase from Pyrococcus horikoshii OT3: structure determination and biochemical characterization of PH1645.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.146: ADP-specific phosphofructokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A T336 L421 V422 L431 I435 T346 L431 V432 L441 I445
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008443 phosphofructokinase activity
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0043844 ADP-specific phosphofructokinase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006000 fructose metabolic process
GO:0006096 glycolytic process
GO:0016310 phosphorylation
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3drw, PDBe:3drw, PDBj:3drw
PDBsum3drw
PubMed19553681
UniProtO59355|K6PF_PYRHO ADP-specific phosphofructokinase (Gene Name=pfkC)

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