Structure of PDB 3dp4 Chain A

Receptor sequence
>3dp4A (length=258) Species: 10116 (Rattus norvegicus) [Search protein sequence]
RTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKL
SIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFS
KPFMSLGISIMIKKGTPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIA
VYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQR
KPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNK
WWYDKGEC
3D structure
PDB3dp4 Structure of the S1S2 glutamate binding domain of GLuR3.
ChainA
Resolution2.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AMQ A Y61 L90 T91 R96 G141 S142 T143 L192 E193 M196 Y58 L87 T88 R93 G138 S139 T140 L189 E190 M193 MOAD: Kd=43nM
PDBbind-CN: -logKd/Ki=7.37,Kd=43nM
BindingDB: Ki=21nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:3dp4, PDBe:3dp4, PDBj:3dp4
PDBsum3dp4
PubMed19003990
UniProtP19492|GRIA3_RAT Glutamate receptor 3 (Gene Name=Gria3)

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