Structure of PDB 3do7 Chain A

Receptor sequence
>3do7A (length=296) Species: 10090 (Mus musculus) [Search protein sequence]
SCTLGRLVSPGPCPRPYLVITEQPKQRGMRFRYECEGRSAGSILGESSTE
ASKTQPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGVCR
VRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAGSLKNHQ
EVDMNVVRICFQASYRDQQGHLHRMDPILSEPVYDKKSTNTSELRICRIN
KESGPCTGGEELYLLCDKVQKEDISVVFSTASWEGRADFSQADVHRQIAI
VFKTPPYEDLEISEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSY
3D structure
PDB3do7 NF-kapppaB p52:RelB heterodimer uses different binding modes to recognize different kappaB DNA
ChainA
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y120 C122 E123 R209 K210 T276 K308 Q334 Y33 C35 E36 R122 K123 T189 K221 Q247
BS02 dna A R117 R119 R125 A127 S129 R30 R32 R38 A40 S42
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3do7, PDBe:3do7, PDBj:3do7
PDBsum3do7
PubMed
UniProtQ04863|RELB_MOUSE Transcription factor RelB (Gene Name=Relb)

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