Structure of PDB 3dnf Chain A

Receptor sequence
>3dnfA (length=281) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
MVDIIIAEHAGFCFGVKRAVKLAEESLKESQGKVYTLGPIIHNPQEVNRL
KNLGVFPSQGEEFKEGDTVIIRSHGIPPEKEEALRKKGLKVIDATCPYVK
AVHEAVCQLTREGYFVVLVGEKNHPEVIGTLGYLRACNGKGIVVETLEDI
GEALKHERVGIVAQTTQNEEFFKEVVGEIALWVKEVKVINTICNATSLRQ
ESVKKLAPEVDVMIIIGGKNSGNTRRLYYISKELNPNTYHIETAEELQPE
WFRGVKRVGISAGASTPDWIIEQVKSRIQEI
3D structure
PDB3dnf Structure of (E)-4-Hydroxy-3-methyl-but-2-enyl Diphosphate Reductase, the Terminal Enzyme of the Non-Mevalonate Pathway.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.17.7.4: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 F3S A C13 G15 C96 T165 C193 A195 C13 G15 C96 T165 C193 A195
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0051745 4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0016114 terpenoid biosynthetic process
GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
GO:0050992 dimethylallyl diphosphate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3dnf, PDBe:3dnf, PDBj:3dnf
PDBsum3dnf
PubMed19035630
UniProtO67625|ISPH_AQUAE 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (Gene Name=ispH)

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