Structure of PDB 3dhv Chain A

Receptor sequence
>3dhvA (length=498) Species: 226900 (Bacillus cereus ATCC 14579) [Search protein sequence]
KLLEQIEKWAAETPDQTAFVWRDAKITYKQLKEDSDALAHWISSEYPDDR
SPIMVYGHMQPEMIINFLGCVKAGHAYIPVDLSIPADRVQRIAENSGAKL
LLSATAVTVTDLPVRIVSEDNLKDIFFTHKGNTPNPEHAVKGDENFYIIY
TSPKGVQITYNCLVSFTKWAVEDFNLQTGQVFLNQAPFSFDLSVMDIYPS
LVTGGTLWAIDKDMIARPKDLFASLEQSDIQVWTSTPSFAEMCLMEASFS
ESMLPNMKTFLFCGEVLPNEVARKLIERFPKATIMNTYGPTEATVAVTGI
HVTEEVLDQYKSLPVGYCKSDCRLLIMKEDGTIAPDGEKGEIVIVGPSVS
VGYLGSPELTEKAFTMIDGERAYKTGDAGYVENGLLFYNGRLDFQIKLHG
YRMELEEIEHHLRACSYVEGAVIVPIKKGEKYDYLLAVVVPGEHSFEKEF
KLTSAIKKELNERLPNYMIPRKFMYQSSIPMTPNGKVDRKKLLSEVTA
3D structure
PDB3dhv Crystal structure and enantiomer selection by D-alanyl carrier protein ligase DltA from Bacillus cereus.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T152 F172 T297 E298 K403 R408 K492
Catalytic site (residue number reindexed from 1) T151 F166 T291 E292 K397 R402 K486
Enzyme Commision number 6.2.1.54: D-alanine--[D-alanyl-carrier protein] ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DAL A F196 D197 C269 G295 V301 K492 F190 D191 C263 G289 V295 K486
BS02 AMP A G270 E271 V272 T293 Y294 T297 V321 D383 Y394 R397 G264 E265 V266 T287 Y288 T291 V315 D377 Y388 R391
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0047473 D-alanine [D-alanyl carrier protein] ligase activity
Biological Process
GO:0070395 lipoteichoic acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3dhv, PDBe:3dhv, PDBj:3dhv
PDBsum3dhv
PubMed18847223
UniProtQ81G39|DLTA_BACCR D-alanine--D-alanyl carrier protein ligase (Gene Name=dltA)

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