Structure of PDB 3dba Chain A

Receptor sequence
>3dbaA (length=171) Species: 9031 (Gallus gallus) [Search protein sequence]
RLEECNILFELLTEIQDEAGSMEKIVHKTLQRLSQLLAADRCSMFICRSR
NGIPEVATRLLNVTPTSKFEDNLVNPDKETVFPLDIGIAGWVAHTKKFFN
IPDVKKNNHFSDYLDKKTGYTTVNMMAIPITQGKEVLAVVMALNKLNASE
FSKEDEEVFKKYLNFISLVLR
3D structure
PDB3dba The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change.
ChainA
Resolution2.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.35: 3',5'-cyclic-GMP phosphodiesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 35G A S97 F99 L115 N116 I142 A143 F164 S165 L168 Y174 T176 L197 S43 F45 L61 N62 I88 A89 F110 S111 L114 Y120 T122 L143 PDBbind-CN: -logKd/Ki=8.00,Kd=10nM
External links
PDB RCSB:3dba, PDBe:3dba, PDBj:3dba
PDBsum3dba
PubMed18614542
UniProtP52731|PDE6C_CHICK Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (Gene Name=PDE6C)

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