Structure of PDB 3dam Chain A

Receptor sequence
>3damA (length=467) Species: 35935 (Parthenium argentatum) [Search protein sequence]
KPLREIPGSYGIPFFQPIKDRLEYFYGTGGRDEYFRSRMQKYQSTVFRAN
MPPGPFVSSNPKVIVLLDAKSFPILFDVSKVEKKDLFTGTYMPSTKLTGG
YRVLSYLDPSEPRHAQLKNLLFFMLKNSSNRVIPQFETTYTELFEGLEAE
LAKNGKAAFNDVGEQAAFRFLGRAYFNSNPEETKLGTSAPTLISSWVLFN
LAPTLDLGLPWFLQEPLLHTFRLPAFLIKSTYNKLYDYFQSVATPVMEQA
EKLGVPKDEAVHNILFAVCFNTFGGVKILFPNTLKWIGLAGENLHTQLAE
EIRGAIKSYGDGNVTLEAIEQMPLTKSVVYESLRIEPPVPPQYGKAKSNF
TIESHDATFEVKKGEMLFGYQPFATKDPKVFDRPEEYVPDRFVGDGEALL
KYVWWSNGPETESPTVENKQCAGKDFVVLITRLFVIELFRRYDSFEIELG
ESPLGAAVTLTFLKRAS
3D structure
PDB3dam Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.92: hydroperoxide dehydratase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM A K88 F92 L109 H119 K123 N276 T277 G280 W410 N412 K424 C426 A427 V432 K83 F87 L104 H114 K118 N271 T272 G275 W405 N407 K419 C421 A422 V427
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0009978 allene oxide synthase activity
GO:0016491 oxidoreductase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016829 lyase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0009695 jasmonic acid biosynthetic process
GO:0016125 sterol metabolic process
GO:0031408 oxylipin biosynthetic process
Cellular Component
GO:0009535 chloroplast thylakoid membrane
GO:0009941 chloroplast envelope

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3dam, PDBe:3dam, PDBj:3dam
PDBsum3dam
PubMed18787124
UniProtQ40778|C74A2_PARAR Allene oxide synthase (Gene Name=CYP74A2)

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