Structure of PDB 3d8n Chain A

Receptor sequence
>3d8nA (length=250) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence]
TMRIAYAGLRRKEEFKALAEKLGFTPLLFPVQATEKVPVPEYRDQVRELA
QGVDLFLATTGVGVRDLLEAGKALGLDLEGPLAKAFRLARGAKAARALKE
AGLPPHAVGDGTSKSLLPLLPQGRGVAALQLYGKPLPLLENALAERGYRV
LPLMPYRHLPDPEGILRLEEAVLRGEVDALAFVAAIQVEFLFEGAKDPKA
LREALNTRVKALAVGRVTADALREWGVKPFYVDETERLGSLLQGFKRALQ
3D structure
PDB3d8n Structure and mechanistic implications of a uroporphyrinogen III synthase-product complex.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.75: uroporphyrinogen-III synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UP3 A R9 Q31 T59 G60 V61 K92 Y131 G132 H157 V182 A183 A184 I185 Q186 R10 Q32 T60 G61 V62 K93 Y132 G133 H158 V183 A184 A185 I186 Q187
Gene Ontology
Molecular Function
GO:0004852 uroporphyrinogen-III synthase activity
GO:0016829 lyase activity
Biological Process
GO:0006779 porphyrin-containing compound biosynthetic process
GO:0006780 uroporphyrinogen III biosynthetic process
GO:0033014 tetrapyrrole biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3d8n, PDBe:3d8n, PDBj:3d8n
PDBsum3d8n
PubMed18651750
UniProtQ72KM1

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