Structure of PDB 3d6z Chain A

Receptor sequence
>3d6zA (length=277) Species: 1423 (Bacillus subtilis) [Search protein sequence]
KESYYSIGEVSKLANVSIKALRYYDKIDLFKPAYVDPDTSYRYYTDSQLI
HLDLIKSLKYIGTPLEEMKKAQDLEMEELFAFYTEQERQIREKLDFLSAL
EQTISLVKKRMKRQMEYPALGEVFVLDEEEIRIIQTEAEGIGPENVLNAS
YSKLKKFIESADGFTNNSYGATFSFQPYTSIDEMTYRHIFTPVLTNKQIS
SITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIADRQLTVVSDV
YELIIPIHYSPKKQEEYRVEMKIEILD
3D structure
PDB3d6z Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A S7 I8 G9 R23 Y42 R43 S6 I7 G8 R22 Y41 R42 PDBbind-CN: Kd=0.96uM
BS02 RHQ A P144 Y152 Y170 G171 A172 I182 F224 E253 I255 Y268 P143 Y151 Y169 G170 A171 I181 F223 E252 I254 Y267
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3d6z, PDBe:3d6z, PDBj:3d6z
PDBsum3d6z
PubMed18658145
UniProtP39075|BMRR_BACSU Multidrug-efflux transporter 1 regulator (Gene Name=bmrR)

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